The Colon Cancer Project - Conventional, Experimental and Alternative Therapies

Last updated June 2, 2003

Disclaimer and Webmaster Contact Information - Click here! I am NOT a doctor and have no medical training!

News Note 6/2/03 The Colorectal Cancer Network is an excellent organization which is involved in (among other things) legislative efforts on behalf of colon cancer patients, promoting aggressive awareness, screening, and early detection programs, and support groups . They are sponsoring a Survivor's Conference September 12-14, 2003 in Baltimore, MD. I expect it to be quite good, an opportunity to attend informative presentations by oncologists and other medical professionals, as well as meeting other colon cancer survivors/caregivers from across the country.
Website Updates

6/4/03 Stereotactic Radioablation at Indiana University
6/2/03 I've been a bit lazy in adding new links to this webpage lately, because I found it was a lot easier to put them here in the links section of the Yahoo Group Colon Cancer Support . New links will eventually be incorporated into the website, but until then you'll have to look on Yahoo!

4/9/03 3rd Annual CCA Conference (April 2003) - Review
11/24/02 Psycological Support
10/28/02 Hepatic Arterial Infusion Discussion
10/18/02 Conformal Radiation Discussion
10/18/02 RFA Discussion
8/3/02 Alternative Therapy Discussion


Interesting Abstracts (Pubmed) -(Sept-Nov 01) -(Dec 01) -(Jan - Mar 2002) -(Mar - April 2002) -(04-14-02) -(04-20-02)

CAM Abstracts (Pubmed) -(Jan - Mar 2002) -(Mar - ? 2002) - Update Mar 29

Click here: Yahoo! Groups experimentalandunconventional Bulletin Board to post/discuss up-to-date information on conventional treatments (chemo , radiation, etc.), new clinical trials, and alternative/complementary medicine

Click here: Yahoo! Groups Colon_Cancer_Support An open membership forum for colon cancer survivors and caregivers.

BB Postings of Interest from colon_cancer_support

Colon Cancer Diagnosis - What Your Doctor May Not Tell You Online Booklet and Guide to this Site (last updated - 9/17/01)


Site Map
  1. Introduction
  2. My Story - from BB Posts
  3. Getting Started
  4. Psycological Support
  5. Advanced Cancer
  6. Survivor Stories
  7. Where to Go - Major Cancer Centers in the US
  8. Popular Press
  9. Current News
  10. Bulletin Boards
  11. Search Engines
  12. Medical Libraries
  13. Links
  14. Drug Information
  15. Medscape
  16. FDA
  17. Links Collections
  18. Drug Information
  19. Online Books
  20. Medical Journals
  21. Organizations/Conferences
  22. Genetic Testing
  23. Clinical Trials Page
  24. Ideas - Experimental/New Therapies Page
  25. Chemotherapy Page
  26. Conformal Radiotherapy Page
  27. Hyperthermia Page
  28. Total Mesorectal Excision
  29. Therapy for Liver Metastasis
  30. Therapy for Extrahepatic Metastasis
  31. Company Websites Summary
  32. Biologic Agents
  33. AntiAngiogenesis
  34. Alternative/Complementary Therapy
  35. Miscellaneous
  36. Diagnostic Testing
  37. Technical Corner

    Introduction
    After being diagnosed with colon cancer in March, 2001, I began looking for information on the internet about the subject. I was able to quickly locate lots of very good websites with plenty of material about colon cancer diagnosis, prevention, prognosis, chemotherapy, etc., but experienced considerable difficulty in finding a single site which summarized experimental therapies under development specifically oriented to colon cancer in a way that I found useful. I soon discovered that unfortunately my doctors were not always aware of the experimental drugs and trials I was finding, and concluded that if I didn't find out more about these things myself, no one else was going to do it for me. Feeling overwhelmed with unorganized information scattered everywhere, I decided to create for myself an HTML document containing links to the many websites of interest in order to help me organize my own thoughts and research. It occurred to me that this document might be of use to others as well, so I decided to put it up on the Web. You won't find any fancy graphics or other clever programming on this page, as I have little time to create such luxuries. Some sections of the page are better developed than others, reflecting my interests and time to work on them. What I would consider the "best developed" sections would be those on Biologic Agents (Monoclonal Antibodies, Cancer Vaccines) and the sections on Celebrex/Lovastatin (Celebrex is one of the few "alternative therapies" I could find which have serious suggestions of efficacy in the peer reviewed medical literature, although to date there have been no clinical trials proving efficacy in humans for colorectal cancer). If you are interested in "what is going on" with new drug development, but are having a hard time in "putting it all together", you have come to the right place. I plan on updating the page regularly, you can always see the latest date this has occurred at the top. The date you will see next to each item on the page is the date I first located that item - as of that date, the link was working.

    If you would like to e-mail me, my address is altman23@cs.com. I plan on improving the website as I have time, reorganizing and creating seperate pages for some of the topics. Any suggestions for additions to the page or comments are always welcome.

    Keith

    My Story - from Bulletin Board Posts

    Summary

    dx 3/23/01 Stage IV colon cancer with multiple liver mets
    Colon Resection 3/27/01 7cm tumor removed at ileocecal valve, wedge resection of one surface liver met
    Liver Lobectomy (right lobe) 6/28/01 Two diaphragm mets discovered and resected during surgery
    Recurrence #1 discovered 12/11/01 Solitary Liver Met
    Stereotactic Radioablation for liver met 2/2002
    Recurrence #2 May 2002
    Radiofrequency Ablation 8/8/02 (one liver met)
    Surgery (liver resection) 9/26/2002, two liver mets, duodenal met and met on small intestine (all resected)

    Go to the BOTTOM of the list for the beginning

    10/2/02 After Surgery (Sept 26) - Summary of History to Date
    9/25/02 Before Surgery (Sept 26) Post 2
    9/25/02 Before Surgery (Sept 26) Post 1
    8/24/02 Followup from RFA
    8/14/02 No More Stereotactic
    8/11/02 Following RFA (Aug 8)
    7/30/02 Pre RFA (Aug 8)
    6/7/02 No Chemo
    6/7/02 Recurrence #2 Detected
    3/11/02 After Stereotactic Radioablation
    2/4/02 Fraction #1 of 3 - Stereotactic Radioablation
    2/3/02 Before First Fraction of Stereotactic
    1/24/02 Problems with Scans #2
    1/11/02 Problems with Scans #1
    1/8/02 Fitting the Body Frame
    1/5/02 History to Date


    Getting Started

    Here are some general references to help you get started with your search for information. One of the most important sites is the National Cancer Institute Homepage - see their booklet Cancer of the Colon and Rectum . After you've finished that, you will be ready for the more detailed Diagnosis and Staging Page .

  1. 9/22/01 R.A. Bloch Cancer Foundation, Inc Has Free Online Books, "Fighting Cancer", "Cancer, There's Hope", and "Guide for Cancer Supporters"

  2. 6/3/01 Cancer of the Colon and Rectum This is an easy to read overview of colon cancer from the NCI

  3. 6/11/01 Colon and Rectal Cancer - Patient Centered Guide "This information center has been created especially for people with colon or rectal cancer and their families."

  4. 5/20/02 People Living With Cancer - Colorectal Cancer (ASCO Website)

  5. 8/28/01 CRI Helpbook - What to do if Cancer Strikes

  6. 2/10/02 Case Presentation - Colon Cancer

  7. 4/16/01 National Cancer Institute Homepage

  8. 4/17/01 Oncolink - University of PA

  9. 4/20/01 Steve Dunn's Cancerguide I highly recommend this site as a source of information about how to do your own cancer research and an intro to clinical trials

  10. 9/10/02 Cancer Glossary

  11. 12/1/02 Colon Cancer Glossary

  12. 4/9/01 Colon Cancer Treatment PDQ, from NCI This is a much more technical summary of colon cancer from the NCI and might be considered a starting point for the medical literature. If you are just learning about colon cancer, you may want to postpone this one for later. It gives a basic summary of colon cancer: stages, treatment options, clinical trial results, literature summary. It contains some of the nasty "survival" stats, so if you're uncomfortable with that please do not click here. Keep in mind the data they calculate these things from is at least 5 years old and does not take into account the possibility some of the new therapies mentioned in this site may significantly improve survival.

  13. 8/4/02 Diagnosis and Staging of Colon Cancer

  14. 8/29/02 How is Colon and Rectal Cancer Staged?

  15. 1/30/02 Colorectal Cancer - Summary Article from E-Medicine.com

  16. 8/3/02 It's What the Surgeon Doesn't see that Kills the Patient by Paul Sugarbaker

  17. 8/3/02 Outcome Indicators - What's the Prognosis? Cleveland Clinic

  18. 8/3/02 Colorectal Carcinoma ACO Manual

  19. 8/3/02 Colorectal Cancer Treatments

  20. 6/23/01 Therapeutic Options for Treating Advanced Colorectal Cancer Clinical Journal of Oncology Nursing - September/October 2000 - Volume 4, Number 5

  21. 9/10/01 Q&A on Colon Cancer from Cancerbacup.org (UK site)

  22. 9/10/01 Chemotherapy Q&A from Cancerbacup.org (UK site)

  23. 9/10/01 Oncolink FAQ Colon Cancer

  24. 9/10/01 Colon Cancer Alliance FAQ with Questions for your doctor

  25. 12/5/01 CCN Questions for your Doctor

  26. 1/29/02 MedHelp Colon Cancer FAQ (Other FAQs at this site)

  27. 11/04/01 Colon Cancer Alliance

  28. 11/27/01 Colorectal Cancer Network

  29. 6/18/01 CancerIndex: Guide to Internet Resources on Cancer Huge List of Links: Both Patient and Health Professional Genetic Information, Virtual Colonoscopy

  30. 4/23/01 CanSearch: Online Guide to Cancer Resources The purpose of CanSearch is to assist online users in finding Internet cancer resources. CanSearch will take you step by step to each of the storehouses of cancer information

  31. 7/15/01 Cancersource.com News and other information on all cancer types

  32. 7/18/01 Colon Cancer References

  33. 9/3/01 OncologyChannel.com

  34. 5/13/01 CancerChannel.com (Ivanhoe)

  35. 9/19/01 Iressa vs Angiozyme?

  36. 10/2/01 Eating Hints for Cancer Patients FREE online book

  37. 10/7/02 Cancer Information Network

  38. 11/2/02 Colorectal Neoplasia by Carol A. Burke, MD (Cleveland Clinic)

  39. 11/24/02 Cancertalk CancerTalk is dedicated to addressing important and sometimes difficult questions and concerns about cancer and its impact on the lives of many of the people who visit our Web site. Dr. Cha Each edition explores a specific topic through discussion with callers. This series, with audio and text, is co-hosted by radiation oncologist Dr. Christine Cha and medical broadcaster Gina Tuttle.

    Psycological Support

  40. 5/10/02 I wish you enough

  41. 5/28/02 Learning Place Online: Chronic and Serious Illness
    by Arlene Harder , cofounder of The Wellness Community in Pasadena, California (1989) - a support organization for cancer patients. Arlene also ran the now defunct canceronline.org, one of the first websites to offer psycological support for cancer. Many of the illness related articles in thelearningplaceonline are from canceronline.org.

  42. 11/24/02 The Wellness Community - Frankly Speaking About Colorectal Cancer

  43. 11/24/02 Choices in Healing by Michael Lerner -FULL TEXT BOOK-

  44. 11/24/02 Cancerlynx Huge Collection of Articles

  45. 11/24/02 In Defense of Sadness (cancerlynx)

  46. 11/24/02 Practical Advice from A Son (cancerlynx)

  47. 11/24/02 Questions to Ask Before Signing Up for a Clinical Trial (cancerlynx)

  48. 11/24/02 Redefining Failure - A Nurse's View (cancerlynx)

  49. 11/24/02 Second Opinions - A Patient's Thoughts (cancerlynx)

  50. 11/24/02 Second Opinions for Cancer Patients (cancerlynx)

  51. 11/24/02 The Leap of Faith into the Darkness (cancerlynx) There are no studies, no trials, just leaps of faith into the darkness. That's exactly how I felt when I agreed to the protocol my doctor and I worked out together. As I mentioned, I had drug resistance tests done,which is why I chose not to do chemo/Adria right off the bat, although the honor could have been mine. They tested me for everything except tamoxifen and radiation, the two things I FORGOT to request, and which I ended up doing. Leap of Faith.

  52. 11/24/02 The Medical Use of Hope (cancerlynx)

  53. 11/24/02 The Nature and Complexity of Hope (Learningplaceonline.com)

  54. 11/24/02 Hope and the Mind-Body-Spirit Connection (Learningplaceonline.com)

  55. 11/24/02 Treating Metastatic Disease (cancerlynx)Treating metastatic disease is vastly different than treating presumed residual disease in the adjuvant, post-op, newly-diagnosed patient setting. The realistic goal of adjuvant chemo is to rid the patient of the disease. The realistic goal in treating metastatic disease is to beat it back for as long as you can. These goals ARE different.

  56. 11/24/02 Chemo Angels Are you a Cancer Patient? You deserve a little pampering from one of our Angels as you go through this challenging experience. Your personal ChemoAngel will do his/her best to bring a ray of sunshine into your life. Since our service is provided through the postal mail, your location is unimportant. We have many international patients and Angel volunteers!

  57. 11/24/02 Making Treatment Choices (Learningplaceonline.com)

  58. 11/24/02 What to Ask Your Doctor (Learningplaceonline.com)

  59. 11/24/02 Choosing an Oncologist (Learningplaceonline.com)

  60. 11/24/02 Preparing for a Doctor Visit (Learningplaceonline.com)

  61. 11/24/02 Colon Cancer: After Diagnosis (see online booklet, "Living With Colorectal Cancer")

    Advanced Cancer

  62. 6/12/01 Crossing the Creek - A Practical Guide to Dying Process The views expressed in this guide are the opinions and perspectives of the author. They were acquired over years of working with dying people, but do not constitute the only valid perspective on dying process. If the opinions expressed herein clash with your own, stop reading and search for support elsewhere.

  63. 11/24/02 Beyond Indigo Grief and Dying Issues

  64. 11/24/02 Terminal Illness (beyondindigo.com)

  65. 12/1/02 On Death and Dying and Near Death Experiences Especially see the Gilles Bédard's series of interviews on Death and Dying

  66. 11/24/02 Jerome Groopman New Yorker Articles
    Jerome Groopman is an oncologist at Harvard University who has written a series of fascinating articles for the New Yorker magazine about cancer. His latest may (at least as of today - 11/24 - but probably not for long!) be found here Dying Words: How should doctors deliver bad news? I assume it will eventually be put up on the groopman.com site as well.

  67. 12/1/02 Growth House "Growth House, Inc., provides this award-winning portal as your international gateway to resources for life-threatening illness and end of life care. Our primary mission is to improve the quality of compassionate care for people who are dying through public education and global professional collaboration. Our search engine gives you access to the Internet's most comprehensive collection of reviewed resources for end-of-life care."

  68. 6/11/01 Advanced Cancer -Living Each Day This National Cancer Institute booklet was written to help persons who have gone through the struggles of diagnosis, treatment, and, perhaps, recurrence of cancer, persons for whom a cure or long-term remission is no longer likely.

  69. 3/9/02 Home Care Guide for Advanced Cancer

  70. 1/20/02 When a Parent Dies of Cancer Clinical Journal of Oncology Nursing Article

  71. 3/9/02 Five Wishes Five Wishes is a document that helps you express how you want to be treated if you are seriously ill and unable to speak for yourself. It is unique among all other living will and health agent forms because it looks to all of a person's needs: medical, personal, emotional and spiritual. Five Wishes also encourages discussing your wishes with your family and physician.

  72. 5/10/02 Transitions at the End of Life

  73. 5/10/02 Internet Resources

  74. 5/28/02 To Flee Or Not to Flee: The Problem of Denial When Dying

  75. 6/13/02 Living with Dying in America

  76. 6/13/02 In Search of a Good Death AARP

  77. 9/8/02 Pain Due to Cancer

    Survivor Stories

    Colon cancer IS NOT necessarily a death sentence. There are long term survivors of even stage IV disease. Read the stories of those who have been there to find out what it's really like.

  78. 6/11/01 After Treatment and Beyond Survivor Interviews from the Cancer Survivors Network. This is a HUGE collection of survivor stories - there is a lot of good information here.

  79. 4/11/01 Colorectal Cancer: Survivors (MSN) You are not alone! Join colorectal cancer survivors from the Colorectal Cancer Network to talk about their stories and experiences, both good and bad.

  80. 4/17/01 Colon Cancer Alliance. Stage IV Survivor Stories

  81. 6/11/01 Survivor Stories from Steve Dunn's Cancerguide

  82. 6/16/01 Steven Parr's Homepage Steven Parr is a Stage IV colon cancer survivor from England. He was first diagnosed in March, 1996. He has posted his story on this page.

  83. 6/7/01 Dr. Fair's Tumor 10/26/98 New Yorker Magazine. Dr. William R. Fair was chief of the Department of Urologic Surgery at Sloan Kettering before he was diagnosed with colon cancer. He took chemotherapy for a year and his cancer returned. He refused additional chemo (Camptosar) in favor of alternative medicine which apparently halted his tumor growth.

  84. 4/11/01 Story of Shannon Kellum In this amazing story, Shannon was near death from liver failure (very advanced colon cancer mets to the liver), but was pulled back from the brink by a new monoclonal antibody which is currently under review by the FDA and should be on the market in 6 months to a year.

  85. 9/24/01 Robert Vandegrift Homepage Diagnosed Stage IV with liver mets 1996, currently in remission

  86. 6/24/01 TITLE: Long-term survival achieved by resection of metastases in the liver and lung in a patient with recurrent colonic cancer: report of a case. AUTHOR: Suzuki M, Kadoyama C, Otsuji M, Sugiura T, Kimura F, Suwa T, Fujisawa T SOURCE: Surg Today; 30(11):1037-40 2000 UI: 20560354 The patient remains alive 14 years after the initial resection of colonic cancer. This case is considered noteworthy because it demonstrates the potential effectiveness of local adjuvant chemotherapy and the possibility of extended survival in a patient who has undergone resection of both hepatic and pulmonary metastases from colonic cancer

  87. 1/20/02 Cliff's Story I

  88. 1/20/02 Cliff's Story II

  89. 1/20/02 Conformal Radiation Patient Stories

  90. 1/20/02 RF Ablation Patient Stories

  91. 1/29/02 Shared Experience An open, freely searchable listing of first-hand accounts by cancer patients

  92. 2/2/02 Jerry's Page

  93. 3/9/02 Martin's Story Diagnosed in 1993 with stage IV cancer, alive today!

    Where to Go - Major Cancer Centers in the US

  94. 8/4/02 Questionabledoctors.org Questionable Doctors is the only comprehensive, publicly available databank that contains information on doctors who have been disciplined by state medical boards and federal agencies in the past ten years. It contains data on disciplinary actions taken for medical incompetence, misprescribing drugs, sexual misconduct, criminal convictions, ethical lapses and other offenses. Questionable Doctors, unlike other online databanks, allows you to search for a doctor's name before you pay, and includes information on multiple states.

  95. 9/1/02 The American Society of Colon and Rectal Surgeons Find a BOARD CERTIFIED Colorectal Surgeon

  96. 8/5/02 Best Hospitals: CANCER - US News and World Report

  97. 8/30/01 Second Opinion Online Patients Can Pay for an Expert's Assessment Via Computer Along with convenience comes a price tag of $600 per case, which is not covered by insurance providers. Three of Boston's top hospitals recently launched the service to sell second opinions online. Massachusetts General Hospital, Dana Farber Cancer Institute, and Brigham and Women's Hospital's offer links on their homepages to the "Partners Online Specialty Consultation" site. The Cleveland Clinic in Ohio plans to launch a similar service by the end of the year

  98. 9/1/01 Dana Farber Cancer Institute - Second Opinion Online

  99. 4/24/01 Major Cancer Centers in USA List of Internet Sites

  100. 4/28/01 Search Cancer Centers by Geographic Region Links to all NCI Cancer Centers. Map of USA, click on states you want for info

  101. 8/28/01 RESOURCE DIRECTORY Medical Facilities for Diagnosis, Treatment or Second Opinions

  102. 4/23/01 Guide to Internet Resources for Cancer USA Cancer Resources by State

  103. 9/22/01 Worldwide List of Cancer Centers

  104. 6/19/01 FREE PLANE TRANSPORTATION for patients undergoing treatment at recognized cancer centers

  105. 5/13/01 Healthgrades.com Ratings for Hospitals. Info on "How to choose a physician" (see bar on left side). Click on "Hospitals" under "Get ratings". On left side of new page, for "Provider Search" choose "CANCER CENTERS". Then follow the directions, choose "search by cancer type" "colon and rectal cancer". The search will return the top US cancer centers specializing in colon and rectal cancer treatment

  106. 5/13/01 Healthpages.com Look up doctors background

    Popular Press Overview

    These are a few stories from the "popular press" that I found interesting and informative.

  107. 12/5/01 Vessels of Death or Life Scientific American article Dec 2001 - the science of angiogenesis

  108. 3/9/02 Scientific American Sept 1996 - "What you Need to Know About Cancer"

  109. 5/23/01 Unraveling Cancer Barrons May 19, 2001 New technologies and treatments will soon render cancer controllable. The search for a cure goes on By JAY PALMER Alternate BB Copy

  110. 5/20/01 Hyped drugs might not be a cure, but they may keep tumors in check May 13 2001 On the Cutting Edge: Anti-angiogenesis agents still very alive "We need to redefine treatment success," Li says. "Just stabling the disease may mean success... and may give us time to give a patient other chemotherapy drugs in combination." Alternate BB Copy

  111. 5/20/01 Vaccines Halt Tumors in Their Tracks Best Vaccine Results from 2001 May ASCO meeting May 28, 2001 Alternate BB Copy

  112. 1/30/02 Growth Factor Receptor Signaling Critical To Intestinal Tumor Development, Studies Show

  113. 9/6/02 Monoclonal Antibodies Zero in on Cancer

  114. 9/6/02 CureToday.com free online news

    Current News

    I look at these every day for a quick summary of current news. I have a separate section for Alternative Medicine News

  115. 11/4/02 Newsrx.com

  116. 3/31/02 Northern Light Current News

  117. 12/20/01 DG Dispatch

  118. 12/20/01 Ivanhoe News Flash

  119. 5/19/01 Reuters News Articles - Current News and Cancer Archives of Past Months

  120. 12/5/01 Reuters Health (Professional)

  121. 12/5/01 Excite Health

  122. 10/17/01 Sciencedaily.com Science News

  123. 7/6/01 Auntminnie.com Radiology News

  124. 6/12/01 PR Newswire Has news about biotech companies and other new developments. Can search the last 3 business days for cancer related material

  125. 9/6/02 CureToday.com free online news

  126. 6/13/02 Nature - Oncology

  127. 8/28/02 Medline search of (Colon OR Colorectal OR chemoprevention OR angiogenesis) AND cancer

  128. 4/19/01 Yahoo Cancer News

  129. 2/2/02 Cancer Headlines Intelihealth.com

  130. 4/19/01 Pre Defined Cancerlit Topic Searches. Colon Cancer Abstracts for each Month

  131. 4/18/01 Biospace Breaking news on Colon Cancer from biotech and pharmaceutical companies

  132. 9/18/01 News from CancerHope

  133. 7/11/01 Medscape Hematology Oncology News

  134. 11/13/01 Colorectal Cancer Week

  135. 11/13/01 Pharmaceutical Online News

  136. 7/12/01 PharmaLive Drugs in Development News from the Pharmaceutical Industry: new websites, drugs in development, recent discoveries, trial results

  137. 7/16/01 Colon Cancer Treatment News from Cancerconsultants.com

  138. 7/19/01 Colon Cancer Abstracts from Gastroenterology

  139. 5/05/01 healthology.com

  140. 4/9/01 CBS Health Watch Latest News

  141. 4/17/01 Health Channel

  142. 4/19/01 MSNBC Cancer News

  143. 4/17/01 MSN Colorectal Cancer News

  144. 4/22/01 Cybermedtrials.com Daily News

  145. 5/07/01 Medicine Online - Daily Breaking Oncology News

    Bulletin Boards



  146. 1/31/02 Yahoo! Groups Colon_Cancer_Support An open membership forum for colon cancer survivors and caregivers.

  147. 1/31/02 Yahoo! Groups experimentalandunconventional Bulletin Board to post/discuss up-to-date information on conventional treatments (chemo , radiation, etc.), new clinical trials, and alternative/complementary medicine

  148. 4/24/01 Lycos Web MD Colorectal Cancer Support Group

  149. 11/04/01 Colon Cancer Alliance Chat

  150. 1/31/02 ACOR Colon Cancer Discussion List

  151. 2/2/02 Cancer Alternatives "We are about 40 primarily colon cancer patients, most of whom have been through surgery and chemo. The focus of our group is intelligent discussion of alternative and complementary approaches to cancer" Intro to what this group is about *** More info

  152. 1/31/02 Life Extension Foundation Forums An Alternative/Complementary site. The LEF sells supplements, so although these forum may not be entirely objective, there is still some good info there. The longtime moderator recently resigned (due to issues surrounding this) to devote more time to his personal webpage Tom's Page He is NOT a cancer patient, so there is no special info regarding that topic.

  153. 5/19/02 Yahoo! Groups Cancer Cured - Alternative Cancer Therapies

  154. 5/19/02 Yahoo! Groups Cancercure (Alternative Cancer Therapies)

    Search

    These are references if you want to dig into the literature, drugs, and companies on the cutting edge of development. You can use the Cancerlit search to find all papers on a drug, or all papers by a particular author. To do an "author search" using Cancerlit, simply use the syntax "[au] Cheech and [au] Chong" for example, to find all papers by Cheech and Chong.

  155. 4/20/01 NCI Cancerlit Search Search Cancer Literature by Keywords

  156. 9/10/01 Pub Med Medical Publications Search Engine

  157. 5/14/01 Google Search

  158. 4/29/01 MSN Search

  159. 6/13/01 WebMedLit Plus WebMedLit offers easy access to the best medical journals on the web by scanning premier medical web sites each day and extracting the available citations, abstracts and full-text articles

    Medical Libraries

  160. 6/18/01 TheMedEngine.com Drugs, Med Searches, Publications, News, Medical Libraries, Medical Dictionaries, Medical Reference, etc.

  161. 6/23/01 testuniverse.com Complete Guide to Medical Tests : Test By Name

  162. 9/3/01 Lab Tests Online

  163. 9/3/01 HealthAnswers.com Library with Procedures and Tests Explained

  164. 6/23/01 MD Advice.com Health Library, Drug Information, Medical News, Ask an Expert, Condition Centers, etc.

  165. 6/10/01 cancernetwork.com (registration required) For health professionals. Daily news, Library with online journals and textbooks, questions from doctors about cases

  166. 6/16/01 MedicineNet.com Focus on Cancer MedicineNet also has a Library: Diseases and Conditions, Procedures and Tests, Medications, MedTerms Dictionary, Cancer News

  167. 10/27/01 Nurse's PDR resource center

  168. 6/22/01 Vcure.com Health Channels, including cancer and colorectal cancer. Also has good "drug index" listing side effects, etc of all drugs on the market.

  169. 4/17/01 Medicine Online - Colon Cancer Information Library (Physician Oriented) - Daily News, Medline Search, PDQ Website

  170. 4/9/01 MedlinePlus Drug Information, Medical Dictionary, Doctor Directory

  171. 6/3/01 HealthCentral Library Drug, Disease, Surgery, Symptom Library

  172. 1/30/02 E-Medicine.com

  173. 10/2/01 Cancercare.org

  174. 10/19/01 The Pathology Guy -- Online Help

  175. 3/16/02 The Biopsy Report - a Patient Guide How to interpret a biopsy report

  176. 3/22/02 How to Read a Paper

  177. 6/2/02 Medstudents.com

    Collections of Links

  178. 7/16/01 OncoLynx Huge Collection of References: Organizations, Journals, Databases, Pharmaceuticals

  179. 9/18/01 Cancerlinks Large Collection of Links

  180. 9/18/01 Surgical Procedures, Operative Huge Collection of Links

  181. 10/2/01 Cancer Related Links

  182. 9/15/01 GILinx.com Colon Cancer Articles

  183. 3/11/02 Links to Cancer Resources

    Drug Information

    The BIOSPACE website is the best place to go to find out about pharmaceutical companies, drugs in development, etc. - it has lists by company or drug

  184. 4/18/01 Biospace.com Info from the pharmaceutical industry

  185. 4/18/01 Biospace Listing of Colon Cancer Drugs in Development

  186. 4/18/01 Biospace Complete list of all Pharmaceutical Companies Click on Company to see drugs and trials by that company

  187. 9/15/01 BC Cancer Agency Drug Database

  188. 10/27/01 Anticancer Agents According to Classifications and Their Uses list of all anticancer drugs

  189. 6/22/01 Pharmaceutical Research and Manufacturers of America (PhRMA) Homepage

  190. 6/22/01 Listing of All Cancer Drugs in Development from the Pharmaceutical Research and Manufacturers of America (PhRMA)

  191. 6/18/01 Pharmaceutical Online Marketplace for Industry Professionals

  192. 11/13/01 Decision Resources Pharmaceutical Industry Analysis

    Medscape Links

  193. 6/10/01 Medscape Resource Center - Colorectal Cancer (Registration Required) Medscape's Colorectal Cancer Resource Center is a collection of the latest medical news and information on colorectal cancer prevention, diagnosis and therapy. This resource includes News, Conference Summaries, Ask the Expert Forum, Articles, Editorials, Journal Scans, MEDLINE Abstracts, Links to government and professional organizations, Practice Guidelines, Future Conferences and a Clinical Tool from the Harvard Center for Cancer Prevention to assess an individual's Colorectal Cancer Risk.

  194. 6/10/01 Fighting the Odds: Advances in Colorectal Cancer Diagnosis and Treatment Medscape (registration required) May 14, 2001 ASCO Meeting. Summary of latest Advances. Importance of Microsatellite Instability The Benefits of Cyclo-oxygenase (COX)-2 Inhibition, Controversial Issues in Chemotherapy Treatment, The Value of "Drug Holidays"

  195. 7/11/01 Conference Report Cell Death: New Targets Come to the Fore 2nd International Conference on Mechanisms of Cell Death and Disease: Advances in Therapeutic Intervention June 2-6, 2001 low dose metronomic chemotherapy + COX 2 inhibitors

  196. 7/11/01 Medscape Molecular Medicine News

  197. 4/20/02 Medscape Journals

  198. 4/20/02 Scientific Review of Alternative Medicines

  199. 4/20/02 Advances in Colon Cancer Treatment

  200. 4/20/02 Oral Fluoropyrimidines: A Replacement for Intravenous 5-FU?

  201. 4/20/02 Oral Fluoropyrimidines in the Treatment of Breast and Colorectal Cancer: Latest Insights

  202. 4/20/02 Oral Oncology Products: Barriers to Successful Adoption

  203. 4/20/02 Evolving Techniques for the Treatment of Hepatic Metastases Chicago, Illinois - October 22-27, 2000

    FDA Links

  204. 6/18/01 FDA - Center for Biologics Evaluation and Research (CBER)

  205. 6/18/01 FDA Links List of FDA links

  206. 7/29/01 FDA Press Releases and Talk Papers

  207. 9/15/01 FDA Product Approvals for Cancer Indications September 2001 through June 1996 Listed by Approval Date

  208. 9/15/01 FDA Approved Indications for Cancer Drugs

  209. 9/15/01 FDA Product Approvals by Cancer Indications September 2001 through June 1996 by Cancer Type

  210. 10/3/01 MedWatch FDA Adverse Event Reporting

    Online Textbooks

  211. 1/29/02 First Principles of Gastroenterology Online Textbook

  212. 10/2/01 Electronic Books - Free Online

  213. 10/2/01 Free Online Textbooks

  214. 10/2/01 Gray's Anatomy --- Digestive System

  215. 6/20/2001 The Merck Manual Home Edition General Medical Reference (not just cancer)

  216. 3/18/2002 Cancer Medicine e.5 online Cancer Medicine is widely considered to be one of the leading references in oncology. This comprehensive, mult-disciplinary volume includes completely updated sections on biology, etiology, pathology, imaging, intervention, radiotherapy, chemotherapy, biotherapy, and prevention of neoplastic diseases Whole book is online FREE!!!

    Medical Journals

    Most medical journals do not have free access to online articles without being a subscriber - some do, however, and I've included both types here. You can usually view the abstracts each month for the journals which do NOT have access to full articles to at least get an idea of what is going on for the month.

  217. 7/16/01 Listing of On Line Cancer Journals

  218. 7/19/01 Free Medical Journals

  219. 3/28/02 Online Directory of Medical Journals

    Full Text Access

  220. 7/11/01 Medscape Oncology Journals

  221. 7/12/01 Journal of Clinical Investigation Archives On Line Cancer Articles

  222. 7/11/01 Medscape Journal of Hematology-Oncology

  223. 7/16/01 CA - A Cancer Journal for Clinicians Free Text Access American Cancer Society

  224. 7/16/01 Cancer Control Journal Free Text Access H Lee Moffitt Cancer Center and Research Institute

  225. 8/30/01 The American Surgeon Archives - Free

  226. 9/6/01 Clinical Journal of Oncology Nursing

  227. 11/06/01 Japanese Journal of Clinical Oncology Free Online Journal

  228. 8/17/01 Alternative Medicine Review

    Abstract Only Access

  229. 7/15/01 New England Journal of Medicine Subscriber only for Full Text Access. Free abstracts of all articles

  230. 7/15/01 Journal of Gastroenterology Subscriber only for Full Text Access. Free abstracts of all articles

  231. 7/15/01 The Lancet - Oncology (Registration Required)

  232. 4/19/01 Journal of Clinical Oncology Archives

  233. 4/19/01 Journal of Cancer Research and Clinical Oncology Archives

  234. 6/5/01 Journal of the National Cancer Institute

  235. 11/26/01 International Journal of Hyperthermia

  236. 11/26/01 European Journal of Cancer

  237. 11/27/01 AACR Journals Online

  238. 11/27/01 Clinical Cancer Research (AACR)

  239. 11/27/01 Cancer Research (AACR)

  240. 11/27/01 Cell Differentiation and Growth (AACR)

  241. 11/27/01 Molecular Cancer Therapeutics (AACR)

  242. 3/24/02 Proceedings of the National Academy of Sciences

    Organizations/Conferences

  243. 1/2/02 Medscape Conference Coverage

  244. 7/21/01 List of Oncology Associations/Societies and Cancer Centers

  245. 7/7/01 American Gastroenterological Association

  246. 7/6/01 American Society of Gene Therapy
    Previous Meeting Abstracts (All)
    2001 Abstracts ASGT (May 30-June 3)

  247. 5/02/01 ASCO Homepage
    2001 Abstracts ASCO (May)
    2002 Abstracts ASCO (May)

  248. 7/12/01 American Association for Cancer Research
    2001 Conference Schedule AACR-NCI-EORTC (Oct)
    2001 Abstracts AACR-NCI-EORTC (Oct)
    AACR/AACR-NCI-EORTC Abstracts All Years

  249. 11/18/01 Federation of European Cancer Societies
    List of FECS Conferences
    2001 Abstracts EECO (European Cancer Conference) (Oct 21)
    ECCO 11 MEDSCAPE Coverage - New Targets and New Drugs
    Archived Medscape Article

  250. 11/06/01 American Society for Therapeutic Radiology and Oncology
    2001 Abstracts ASTRO

  251. 10/3/01 CENTER FOR MIND-BODY MEDICINE COMPREHENSIVE CANCER CARE
    Previous Meeting Abstracts

  252. 7/12/01 Biotechnology and Pharmaceutical Development Meetings and Seminars Calendar

  253. 7/12/01 Upcoming Pharmaceutical Conferences (from Strategic Research Institute)

  254. 6/12/01 Anti-Cancer Drug Discovery and Development Summit June 11, 2001 ORGANIZED INTO FIVE SECTIONS: NEW MOLECULAR TARGETS THERAPEUTIC ANTIBODIES APPLIED GENOMICS IN CANCER ANGIOGENIC ADVANCES NOVEL THERAPEUTICS

  255. 9/22/01 Colorectal Cancer Association of Canada

  256. 1/21/02 International Society for Preventive Oncology

    Genetic Testing Go to Page



    Clinical Trials Page Go to Page



    Ideas - Experimental/New Therapies Page Go to Page

    Chemotherapy Go to Page

    Conformal Radiotherapy Page Go to Page

    Therapy for Liver Metastasis Go to Page

    Most patients with late stage colon cancer at some time or another will have liver metastases. There are several ways of dealing with these: Chemotherapy, Surgery, RF Ablation, and Cryotherapy. It would appear that RF ablation is overtaking Cryotherapy as the main "nonsurgical" method of liver met removal.

    Therapy for Extrahepatic Metastisis

    Therapy for Lung Metastisis
    also see Radiation Therapy

  257. 9/13/01 Pulmonary metastasectomy: might the type of resection affect survival? Mineo TC, Ambrogi V, Tonini G, Nofroni I. J Surg Oncol 2001 Jan;76(1):47-52 CONCLUSIONS: The type of resection did not disclose statistically significant differences on survival. Minimal surgery, especially by laser device, is recommended for less morbidity.

  258. 7/7/01 Radiosurgery device shows promise in treating nonresectable lung cancers A radiosurgery instrument, known as the CyberKnife, may offer an additional treatment option for patients with nonresectable forms of lung cancer. Dr. Crownover said that "anyone who has non-small cell lung cancer or metastatic disease is potentially eligible for the study." However, "the tumor has to be less than 5 cm and the patient must not have had prior radiation to the area," he noted. In addition, "if the patient appears to be a surgical candidate then that is the route they usually go," he said.

  259. 8/30/01 Cryotherapy might be first-line treatment for early lung cancer Thursday, Aug 9 2001 Cryotherapy performed through a rigid bronchoscope is both safe and effective in the treatment of patients with early lung cancer, French researchers have found. Dr. Jean-Michel Vergnon, of Hopital Nord in Saint-Etienne, France, and a multicenter team tested the safety and long-term efficacy of cryotherapy in 35 patients with histologically confirmed early superficial bronchogenic carcinoma, seven of whom had lesions at multiple sites. A complete histologic response was noted in 32 patients (91%) at 1 month and in the same number at 1 year, with "no severe adverse effects," Dr. Vergnon's team reports in the July issue of Chest. In seven of these patients, local recurrence was observed within 4 years. Of 22 patients for whom followup data were available at 48 to 89 months, 11 were still alive.

    Intraperitoneal Chemotherapy Go to Page

    Company Websites

    As noted earlier, if you want to find out about clinical trials for a drug, you should identify the company manufacturing the drug, locate the company website and contact information, and give them a call. Here, I have collected links for a number of companies with CC drugs in development. I have found if you are trying to follow a particular drug's development process, the "stock" BB's are often the best source of information - they have all sorts of rumors and info floating around sometimes weeks before it is officially released. So for each company I have included links to the Yahoo message board, and the Raging Bull message board. I have also included a link to the "PR Newswire" daily news.

  260. 4/18/01 Immunogen (IMGN)     News     YMsg     RBMsg
    vhuC242-DM1/SB-408075

  261. 4/28/01 Sugen (PHA)     News     YMsg     RBMsg
    Sugen is Owned by Pharmacia. Currently developing SU5416 (anti angiogenesis)

  262. 4/27/01 Genentech (DNA)     News     YMsg     RBMsg
    Anti-VEGF (also called Avastin)

  263. 4/11/01 ImClone Systems (IMCL)     News     YMsg     RBMsg
    C225

  264. 4/18/01 Entremed (ENMD)     News     YMsg     RBMsg
    Endostatin, Angiostatin

  265. 4/29/01 Abgenix (ABGX)     News     YMsg     RBMsg
    ABX-EGF

  266. 4/29/01 Immunex (IMNX)     News     YMsg     RBMsg
    Prostate Cancer. Agreement with ABGX

  267. 5/02/01 AstraZeneca (AZN)     News     YMsg     RBMsg
    Irissa - small molecule anti angiogenesis

  268. 5/02/01 Medarex (MEDX)     News     YMsg     RBMsg

  269. 5/04/01 Medigene(MDG)     News     YMsg     RBMsg
    NV1020 Modified Herpes Simplex I virus to replicate in Cancer cells

  270. 5/12/01 Celgene (CELG)     News     YMsg     RBMsg
    Thalomid (Thalidomide)

  271. 5/12/01 Novartis (NVS)     News     YMsg     RBMsg
    Gleevec

  272. 5/13/01 Cell Genesis (CEGE)     News     YMsg     RBMsg
    GVAX (Dendrite Cell Vaccine)

  273. 5/14/01 Biomira, Inc. (BIOM)     News     YMsg     RBMsg
    Theratope Vaccine for Breast, Colorectal Cancer

  274. 5/22/01 AVI Biopharm. (AVII)     News     YMsg     RBMsg
    Phase III trials of Avicine CTP-37 Vaccine beginning now

  275. 5/22/01 Theron Biologics ALVAC-CEA/B7.1, a vaccine for colorectal and lung cancers developed as part of Therion's collaboration with Aventis Pasteur, is expected to enter a pivotal Phase II or Phase III clinical trial, subject to the results of a Phase I/II CEA-TRICOM is a recombinant, pox virus-based vaccine that targets carcinoembryonic antigen (CEA) Principal investigator John Marshall, M.D., of Georgetown University Medical Center will lead the study at the Vincent T. Lombardi Cancer Center.    

  276. 6/2/01 Dendreon (DNDN)     News     YMsg     RBMsg
    APC8024

  277. 6/2/01 Immune Response (IMNR)     News     YMsg     RBMsg

  278. 6/2/01 Antigenics (AGEN)     News     YMsg     RBMsg

  279. 6/2/01 Avax (AVXT)     News     YMsg     RBMsg
    Vaccines (not colon yet)

  280. 6/2/01 Progenics Pharmaceuticals (PGNX)     News     YMsg     RBMsg
    Vaccines (not colon yet)

  281. 6/4/01 Geron (GERN)     News     YMsg     RBMsg
    telomerase vaccines - Duke University

  282. 6/19/01 Oxigene (OXGN)     News     BNews     YMsg     RBMsg
    (Combretastatin)
    Biologic Agents Go to Page

    Biologic therapies are one of the hottest areas of Cancer research, because unlike the traditional chemotherapies, they have few side effects. There are 2 main types of biologic agents, monoclonal antibodies and cancer vaccines. Here, I have tried to locate the main drugs/companies and give a few articles from the popular press which caught my attention. Along with the links given in the "Company Websites" section, I have also included links to the "biospace news" on each compound. This is probably the best developed section of my website, as I have focused most of my search on Biologics.

    AntiAngiogenesis Go to Page
    Antiangiogenesis drugs are supposed to work by not allowing the tumor to create new blood vessels, thereby cutting off its supply of blood and killing it. This section contains the references I found, but is not as well developed as the "biologic agents" section because I have been more interested in the antibodies and vaccines lately. I plan to revise this section in the future if I have time.

    Alternative/Complementary Therapies Go to Page

    Miscellaneous Go to Page

    Odds and ends I haven't had time to classify, but which looked interesting

    Diagnostic Testing

  283. 11/4/02 Recommended Colorectal Cancer Surveillance Guidelines by the American Society of Clinical Oncology

  284. 11/4/02 Guidelines from Cleveland Clinic

  285. 11/24/02 Merck Medicus Best Practice Guidelines

  286. 11/24/02 Guidelines for Followup after Resection of Colorectal Cancer -FULL TEXT ARTICLE- Gut,51, (Oct 2002) v3-v5

  287. 11/24/02 ASG Guidelines for Colorectal Screening and Surveillance

  288. 11/24/02 NCCN Practice Guidelines for Colorectal Cancer. Oncology (Huntingt) 2000 Nov;14(11A):203-12 PMID: 11195411 The panel advocates a conservative post-treatment surveillance program for colon and rectal carcinoma patients. Serial CEA determinations are appropriate if the patient is a candidate for aggressive surgical resection, should recurrence be detected. Abdominal and pelvic CT scans should be utilized only when there are clinical indications of possible recurrence. Patients whose disease progresses during 5-FU-based therapy should be treated with irinotecan or encouraged to participate in a phase I or phase II clinical trial.

  289. 11/24/02 Radiologic imaging modalities in the diagnosis and management of colorectal cancer. Hematol Oncol Clin North Am 2002 Aug;16(4):875-95 PMID: 12418053 CT, MRI, and barium enema are used in postoperative follow-up for detecting local recurrence and distant spread. In response to known difficulty in discriminating between normal postoperative changes and tumor recurrence and in determining the nature of certain liver lesions, FDG-PET has been approved for the detection and localization of recurrent colorectal cancer in patients with rising CEA levels and indeterminate findings on